Research Supporting the Cortisol Pump

The below links are compiled research studies supporting the cortisol pumping method and documents that a majority of adrenal patients were able to find better quality of life by the use of an infusion pump that distributed cortisol in a more consistent, bio-identical way that mimicked the body’s natural circadian rhythm.

Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia

Cortisol Pumps Help Reduce Adrenal Crisis

Using the Cortisol Pump to Deliver Cortisol in Addison’s disease

Cortisol Pumps May Be Viable Option to Reduce Adrenal Crisis in Severe Adrenal Insufficiency

New adventures of an old device: Clinic delivers cortisol via the insulin pump

Pulsed glucocorticoid therapy successfully replaced physiological cortisol

Cortisol Pumps May Be Viable Option to Reduce Adrenal Crisis in Severe Adrenal Insufficiency

 Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia

Continuous Subcutaneous Hydrocortisone Infusion versus Oral Hydrocortisone Replacement for Treatment of Addison’s Disease: A Randomized Clinical Trial

Long‐term use of continuous subcutaneous hydrocortisone infusion therapy in patients with congenital adrenal hyperplasia

Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia

Management of Altered Hydrocortisone Pharmacokinetics in a Boy with Congenital Adrenal Hyperplasia Using a Continuous Subcutaneous Hydrocortisone Infusion

Circadian hormone profiles and insulin sensitivity in patients with Addison’s disease: a comparison of continuous subcutaneous hydrocortisone infusion with conventional glucocorticoid replacement therapy

Research Study for Children With Salt Wasting Congenital Adrenal Hyperplasia

Management of adrenocortical insufficiency with continuous subcutaneous hydrocortisone infusion: long-term experience in three patients

Fourteen years’ experience of hydrocortisone pump therapy for cortisol replacement in adrenal insufficiency

Replication of cortisol circadian rhythm: New advances in hydrocortisone replacement therapy

Circadian Rhythm Dosing

Additional Resources

Podcast- Everything you need to know about Cortisol Pumping

Guide to the Cortisol Pump Printable

Cortisol Pump Proposal Letter

Cortisol Pump Insurance Appeal

Cortisol Pumping Advocacy Assistance

More information on cortisol pumping can be found on the cortisol pump advocacy tab on Adrenal Alternatives Foundation website and also in the book Cortisol Pump 101

You can also listen to the podcast episode Everything you need to know about the Cortisol Pump! or download the Guide to the Cortisol Pump.

This information was brought to you by the Adrenal Alternatives Foundation for educational use only and is not meant to provide medical care or advice.